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Antibiotic residues, including tetracyclines, macrolides, and erythromycin, have been detected in commercial honey, potentially stemming from sources such as direct beekeeping practices for disease treatment or environmental contamination. These antibiotic residues in honey raise concerns about potential human health risks, including allergic reactions in susceptible individuals, as well as contributing to antibiotic resistance. This underscores the critical importance of ongoing honey testing, residue monitoring, and food safety measures to ensure safe consumption and regulatory compliance.