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Ractopamine hydrochloride is a phenethanolamine β-adrenoceptor agonist used in pigs and cattle to promote faster growth, leaner meat, and reduced fat deposition. It enhances feed efficiency, allowing livestock to produce more meat from the same amount of feed. The metabolic fate of Ractopamine is similar across target species, laboratory animals, and humans. As a beta-agonist, Ractopamine increases heart rate by mimicking stress hormones, which can lead to significant adverse health effects in treated livestock. Monitoring Ractopamine residues in meat and food products is crucial for food safety and regulatory compliance.